Pain-seq
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Pain-seq
Explore gene expression changes in primary sensory ganglion cell types after exposure to various models of nerve injury or pain. This site hosts data from 141,093 individually sequenced mouse dorsal root ganglion nuclei from different conditions.
Read our paper on
Neuron
.
Browse by gene name
Browse by cell type
This research was performed in the
Renthal Lab
and
Woolf Lab
.
Filters
Gene:
Atf3
Injury models:
Spinal nerve transection (SpNT)
Sciatic nerve crush (Crush)
Sciatic nerve transection (ScNT)
Paclitaxel
Complete Freund’s Adjuvant (CFA)
Cell types:
C-fiber low threshold mechanoreceptor 1 (cLTMR1)
C-fiber low threshold mechanoreceptor 2 (p_cLTMR2)
Peptidergic nociceptor 1 (PEP1)
Peptidergic nociceptor 2 (PEP2)
Non-peptidergic nociceptor (NP)
Nefh+ A-fiber low threshold mechanoreceptor 1 (NF1)
Nefh+ A-fiber low threshold mechanoreceptor 2 (NF2)
Nefh+ A-fiber low threshold mechanoreceptor 3 (NF3)
Sst+ pruriceptor (SST)
Satellite glial cell (Satglia)
Myelinating Schwann cell (schwann_M)
Non-myelinating Schwann cell (schwann_N)
Macrophage
Endothelial
Fibroblast
Submit
Relative expression in naive
Differential expression after injury
Filters
Cell types:
C-fiber low threshold mechanoreceptor 1 (cLTMR1)
C-fiber low threshold mechanoreceptor 2 (p_cLTMR2)
Peptidergic nociceptor 1 (PEP1)
Peptidergic nociceptor 2 (PEP2)
Non-peptidergic nociceptor (NP)
Nefh+ A-fiber low threshold mechanoreceptor 1 (NF1)
Nefh+ A-fiber low threshold mechanoreceptor 2 (NF2)
Nefh+ A-fiber low threshold mechanoreceptor 3 (NF3)
Sst+ pruriceptor (SST)
Satellite glial cell (Satglia)
Myelinating Schwann cell (schwann_M)
Non-myelinating Schwann cell (schwann_N)
Macrophage
Endothelial
Fibroblast
Submit
cell-type-specific genes
injury-induced genes
Renthal Lab
William Renthal
Lite Yang
Hale Building For Transformative Medicine
Brigham and Women's Hospital
60 Fenwood Road
Boston, MA 02115
Woolf Lab
Clifford Woolf
Ivan Tochitsky
FM Kirby Neurobiology Center
Boston Children's Hospital
3 Blackfan Circle
Boston, MA 02115